Healthcare and Biotechnology Strength: What History Suggests About Future Returns
Published: August 12, 2026
This content is for informational purposes only. This should not be construed as solicitation. The general public should consult their financial advisor for additional information related to investment decisions.
For those who have been following the changes in our DALI sector rankings, it should come as no surprise that Healthcare, traditionally viewed as one of the market's more defensive sectors, has made significant progress in recent months.

For those who have been following the changes in our DALI sector rankings, it should come as no surprise that Healthcare, traditionally viewed as one of the market's more defensive sectors, has made significant progress in recent months. Since the beginning of June, the sector has added 63 buy signals and climbed to the #2 position in our sector rankings, firmly establishing itself in overweight territory.

Investors monitoring our Asset Class Group Scores (ACGS) page may have also noticed the strength emerging within Biotechnology, which currently ranks as the top-performing group. As a subsector of Healthcare, Biotechnology encompasses companies that leverage biological processes and living organisms to develop products and therapies aimed at addressing a wide range of human health challenges.

The leadership displayed by Biotechnology has been a key contributor to the Healthcare sector's improving relative strength. Given the strong momentum observed across both areas, we examined the historical forward returns of representative Healthcare and Biotechnology indexes following instances when their average ACGS readings crossed above 4.0 and 5.0. The objective of this study is to determine whether elevated group scores have historically translated into continued future performance.

The table below highlights each instance, excluding signals that occurred within one month of a prior signal, in which the average ACGS reading crossed above 4.0 for both the Biotechnology and Healthcare groups. The iShares Biotechnology ETF TR (IBB.TR) was used as the representative for Biotechnology, while the Health Care Select Sector SPDR ETF TR (XLV.TR) was used as the representative for the Healthcare sector. A few observations stand out:

  • Biotechnology has historically delivered strong forward returns following a move above the 4.0 ACGS threshold. The group generated positive returns in 67% of observations over both the three-month and one-year horizons, with average returns of 5.98% and 14.51%, respectively. Most notably, the average three-month return of nearly 6% suggests that strength within the group has often persisted after the initial signal is generated.
  • The broader Healthcare sector has produced more modest results following similar signals. While forward returns have generally remained positive, the magnitude of those gains has been considerably lower than those observed in Biotechnology. The sector's average one-year return of 5.94% trails the broader market's long-term average, indicating that the signal has historically produced only modest returns.

Taking the analysis a step further, we examined periods in which the average ACGS reading moved above 5.0, a level that reflects even broader participation and stronger underlying group strength. The forward return profile improved significantly at this higher threshold, suggesting that stronger ACGS readings have historically been associated with more favorable performance outcomes. The table below summarizes the results.

  • Biotechnology continued to demonstrate exceptional strength following moves above 5.0. The group generated a positive one-year return in every occurrence, resulting in a 100% success rate and an average one-year gain of 31.23%. These results suggest that periods of broad-based strength within Biotechnology have historically been followed by substantial upside over the subsequent year.
  • The Healthcare sector also produced notably stronger results at the 5.0 threshold versus the 4.0 threshold. While the number of observations is limited, the sector's average one-year return increased to 19.44%, with positive returns in 80% of cases. This suggests that Healthcare has historically maintained strong momentum and generated above-average forward returns when broad participation across industry groups drives the average ACGS reading above 5.0.

For investors seeking exposure to the group's continued strength, the iShares Biotechnology ETF (IBB) may be worth considering. The ETF recently completed a double-top break at $205, completing its second consecutive buy signal and advancing to a new all-time high. The fund reversed back into Xs against the market in June and maintains a strong fund score of 5.71, along with a positive score direction of 1.75. The beta reading of 0.66 is also noteworthy, as it suggests relatively low sensitivity to broader market movements and reinforces the sector's defensive characteristics. The weekly OBOS indicates that the fund is in overbought territory, so wait for a normalization of the 10-week trading band before considering. Initial support is at $190, with additional strong support between $164-$168.

 

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DISCLOSURE

This report is for Internal Use Only and not for distribution to the public. While we make every effort to be free of errors in this report, it contains data obtained from other sources. We believe these sources to be reliable, but we cannot guarantee their accuracy. Investors who use options should read the Options Disclosure Document before making any particular investment decision. Officers or employees of this firm may now or in the future have a position in the stocks mentioned in this report. Dorsey, Wright is a Registered Investment Advisor with the U.S. Securities & Exchange Commission. Copies of Form ADV Part II are available upon request.
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